Definition and causes
Allergic purpura is the most common form of systemic vaskulit in childhood. Vaskulit is an inflammation, ie. inflammatory reaction in the wall of veins. When allergic purpura caused by inflammation of various deposits of immune system components (antibodies, etc.). Karvæggen the smallest vessels in the body (capillaries, arterioler and venoler).
Allergic purpura causing a characteristic skin rash, and many have also symptoms indent gastrointestinal tract and kidneys. The most frequently seen in 2-8 years of age and is more common in boys than girls. The cause of allergic purpura is unknown, but it can be seen in following the progress of a viral infection.
Symptoms of allergic purpura
Hudsymptomer:On the skin creates an rødviolet rash (purpura). Location is determined by gravity, so that wiped out most often found on legs, buttocks and elbow region at the top transient person. Wiped out is beyond the normal skin and can be felt by touch. The size of the rash elements varies from a few millimeters to several centimeters.
Ledsymptomer (arthritis):A large proportion of children (60-80%) have symptoms from one or more links in the form of redness, swelling and / or pain. Usually there are symptoms of knee and / or ankelled, but also from small and albueled.
Gastrointestinal symptoms:Many (75%), the genes in the form of abdominal pain, nausea and vomiting. Rarely seen bleeding from the intestine using and / or Intussusception (a special form of tarmslyng) that begin as powerful tours show abdominal pain.
Kidney symptoms:Half of children develop renal symptoms. Frequently the blood in the urine (haematuria). Rarely seen proteintab through urine (proteinuri), which said the event can be viewed by the urine foam.
General symptoms:Some children will especially in the beginning have a fever, but rarely high (less than 38.5 °) and feel bad adaptation.
Forholdsregeler and diagnosis
If these symptoms develop, the child should be evaluated by a doctor. Initially, the patient should be seen by their own doctor, who then will often refer to the local børneafdeling. When symptoms of Intussusception should immediately seek medical advice as this is a potentially life threatening condition.
The diagnosis is made primarily on medical history and findings at physical examination. The blood tests can measure the various components of the immune system (various antibodies, white blood cells, platelets and so-called reduction reaction) that can support the diagnosis. In rare cases, it is necessary to examine a hudprøve (biopsy) of the microscope to make the diagnosis.
Treatment of allergic purpura
Fever and ledsymptomer is often of itself and can be dealt with, for example. paracetamol (available for example. Panodil in, Pamol and Pinex).
Severe abdominal pain is treated with adrenal cortical hormones. There are often dramatic sound effects. Are given high dose treatment in a week, after which Trappes out.
Kidney symptoms can be treated with adrenal cortical hormones tried and possibly. azathioprin (chemotherapy). Both inhibit the immune response, but the effects on renal symptoms is controversial.
Select and complications
The prognosis is very good. The vast majority of patients recover spontaneously within approximately. a month. Relapse may be seen within the first 2 years.
Intussusception (a special form of tarmslyng) is rare, but serious, and at worst could result in death.
In some of the renal effects developed for this glomerulonefritis, and few of them develop renal failure.